Quinolines and derivatives
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Filtered Search Results
Apexbio Technology LLC OR-486 7659-29-2 50mg
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OR-486 is a small-molecule inhibitor targeting catechol-O-methyltransferase (COMT) It is designed to inhibit COMT activity thereby blocking the enzyme-mediated methylation of catecholamine substrates and regulating neurotransmitter pathways OR-486 exerts its biological activity primarily through enzyme inhibition In biochemical assays OR-486 demonstrates potent inhibitory activity with an IC50 value of approximately 12 nM Based on these pharmacological properties OR-486 holds research potential in investigating catecholamine metabolism neurotransmitter regulation and studies of neuronal pathways as well as serving as a ligand for synthesizing molybdenum(VI)-based metal complexes
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Chemscene ChemScene | 2-Oxo-1,2-dihydroquinoline-6-sulfonyl chloride | 250MG | CS-0080680 | 0.97 | 569340-07-4| MFCD18300284 | 243.67
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ChemScene | 2-Oxo-1,2-dihydroquinoline-6-sulfonyl chloride | 250MG | CS-0080680 | 0.97 | 569340-07-4| MFCD18300284 | 243.67
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Accela Chembio Inc 6-quinolinecarboxylic Acid | 5g | 10349-57-2 | MFCD00047613 | 98% | Shelf Life: 1260 Days | Regular
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6-quinolinecarboxylic Acid | 5g | 10349-57-2 | MFCD00047613 | 98% | Shelf Life: 1260 Days | Regular
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Selleck Chemical LLC Levofloxacin 25mg 100986-85-4 Fluoroquinolone
Levofloxacin (Fluoroquinolone) is a broad-spectrum antibiotic topoisomerase II and topoisomerase IV inhibitor, used to treat respiratory, urinary tract, gastrointestinal, and abdominal infections. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
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Chem-Impex International, Inc. Gatifloxacin | 112811-59-3 | MFCD00895399 | 5G
Gatifloxacin, 112811-59-3, MFCD00895399, 5G
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Medchemexpress LLC HY-50855 10mg Medchemexpress, Silmitasertib CAS:1009820-21-6 Purity:>98%
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Medchemexpress, HY-50855 10mg Silmitasertib CAS:1009820-21-6 Silmitasertib (CX-4945) is an orally bioavailable, highly selective and potent CK2 inhibitor, with IC50 values of 1 nM against CK2α and CK2α'. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Apexbio Technology LLC Amadacycline 389139-89-3 200mg
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Amadacycline (CAS 389139-89-3) is a tetracycline-class antibiotic targeting the bacterial ribosomal 30S subunit It is designed to inhibit bacterial protein synthesis thereby preventing microbial proliferation Amadacycline exerts its biological activity primarily through interference with bacterial translation by inhibiting the 30S ribosomal subunit The exact IC50 value for Amadacycline has not been established Based on these pharmacological properties Amadacycline holds research potential in investigating antibiotic resistance mechanisms bacterial ribosome-targeting strategies and as a candidate in studies evaluating therapeutic agents for complicated skin and skin structure infections
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Medchemexpress LLC CP 339818 (hydrochloride) | 478341-55-8 | 99.6% | 340.89 | 1 MG
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CP 339818 hydrochloride is a non-peptide blocker of Kv1.3 (IC50 = 200 nM) and Kv1.4 channels. It also inhibits HCN channels with IC50s of 18.9 μM and 43.4 μM against HCN1 and HCN4 (high Cl-), respectively. The compound exhibits significantly weaker blocking effects on Kv1.1, Kv1.2, Kv1.5, Kv1.6, Kv3.1-4, and Kv4.2 channels. It can be utilized for studying the physiological functions of HCN and Kv channels.
- Non-peptide Kv1.3 and Kv1.4 channel blocker.
- Inhibits HCN channels (HCN1 and HCN4).
- Selectively blocks Kv1.3, inhibiting human T cell activation.
- Useful for studying physiological functions of HCN and Kv channels.
- Suppresses human T cell activation.
- Effectively blocks remaining outward potassium current in Kv2.1⁻/⁻ β cells.
- Inhibitory effect on HCN1 and HCN4 is weakened in low-concentration Cl- internal solution and is voltage-dependent.
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Medchemexpress LLC Quinine sulfate hydrate | 6119-70-6 | 99.97% | 409.48 | 25 G
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Quinine sulfate hydrate is an orally active alkaloid extracted from cinchona bark, primarily used in anti-malarial studies. It also functions as a potassium channel inhibitor, inhibiting WT mouse Slo3 (KCa5.1) channel currents.
- Orally active alkaloid
- Extracted from cinchona bark
- Used in anti-malarial studies
- Potassium channel inhibitor
- Inhibits WT mouse Slo3 (KCa5.1) channel currents
- Inhibits DENV proliferation and reduces viral RNA/protein levels
- Shows tumor-suppressing effects
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Medchemexpress LLC Quinidine methiodide | 42982-87-6 | C21H27IN2O2 | 5 MG
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Quinidine methiodide is a metabolite of Quinidine, which is known as an antiarrhythmic agent. This product appears as a solid with a white to light yellow color.
- Metabolite of Quinidine
- Antiarrhythmic agent
- Solid appearance
- White to light yellow color
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.36% | 500 MG
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It acts as a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It induces apoptosis and can be utilized for malaria research. It has demonstrated cytotoxicity against MES-SA cells.
- Antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- K+ channel blocker
- Induces apoptosis
- Can be used for malaria research
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Medchemexpress LLC Quinidine (15% dihydroquinidine) | 56-54-2 | 98.4% | 25 G
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Quinidine (15% dihydroquinidine) is an antiarrhythmic agent. It is a potent, orally active, selective cytochrome P450db inhibitor and a K+ channel blocker. It can induce apoptosis and is used for malaria research.
- Antiarrhythmic agent
- Potent, orally active, selective cytochrome P450db inhibitor
- K+ channel blocker with an IC50 of 19.9 μM
- Induces apoptosis
- Can be used for malaria research
- Shows cytotoxicity against MES-SA cells
- Shows effects on the PTZ-induced seizure threshold in vivo
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Apexbio Technology LLC APEXBIO TECHNOLOGY LLC
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5000569422 HYDROQUININE-200MG
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Chemscene CHEMSCENE
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5000579279 HYDROQUINIDINE 5G
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Apexbio Technology LLC Quinidine 56-54-2 250mg
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Quinidine (CAS 56-54-2) is a small-molecule inhibitor targeting sodium (Na ) and potassium (K ) ion channels It is designed to inhibit these ion channel currents thereby modulating cardiac electrophysiological processes Quinidine exerts its biological activity primarily through inhibition of Na and K currents In in vitro studies quinidine demonstrates inhibitory activity with an IC50 of approximately 41 M on the transient outward potassium current (Ik) at a membrane potential of 0 mV Based on these pharmacological properties quinidine holds research potential in the fields of cardiac electrophysiology ion channel pharmacology drug metabolism and drug-drug interaction mechanisms
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